3,4,5-三甲氧基-苯乙酸乙酯合成路线 （共 9 条）
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Major,R.T.; Ohly,K.W.
Journal of Medicinal and Pharmaceutical Chemistry, 1961 , vol. 4, p. 51 - 65
反应条件
1: LiAlH4 / diethyl ether 2: SOCl2, Py View Scheme
参考文献
Major,R.T.; Ohly,K.W.
Journal of Medicinal and Pharmaceutical Chemistry, 1961 , vol. 4, p. 51 - 65
反应条件
hydrazine hydrate in ethanol Heating;
参考文献
Ares; Messier; Kornecki
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 5 p. 1197 - 1201
参考文献
Ares; Messier; Kornecki
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 5 p. 1197 - 1201
参考文献
Katz, Christopher E.; Aube, Jeffrey
Journal of the American Chemical Society, 2003 , vol. 125, # 46 p. 13948 - 13949
反应条件
1: <PhCH2NMe3>OH / tetrahydrofuran; methanol / 12 h / Heating
2: HCl / 1.5 h / Heating
View Scheme
参考文献
Ogura,K. et al.
Bulletin of the Chemical Society of Japan, 1979 , vol. 52, p. 2013 - 2022
反应条件
hydrogenchloride
1.5 h; Heating;
参考文献
Ogura,K. et al.
Bulletin of the Chemical Society of Japan, 1979 , vol. 52, p. 2013 - 2022
反应条件
sulfuric acid
2 h; Heating;
参考文献
Major,R.T.; Ohly,K.W.
Journal of Medicinal and Pharmaceutical Chemistry, 1961 , vol. 4, p. 51 - 65
反应条件
1: (3,4,5-trimethoxyphenyl)acetic acid ethyl ester With lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 1 h;
2: [(Cyanocarbonyl)oxy]ethane in tetrahydrofuran
T=-78 - 20°C;
参考文献
Katz, Christopher E.; Aube, Jeffrey
Journal of the American Chemical Society, 2003 , vol. 125, # 46 p. 13948 - 13949
