6-羟基烟酸甲酯合成路线

Bigge, Christopher Franklin; Bridges, Alexander James; Casimiro-Garcia, Agustin; Fakhoury, Stephen Alan; Lee, Helen Tsenwhei; Reed, Jessica; Schaum, Robert; Schlosser, Kevin Matthew; Sexton, Karen; Zhou, Hairong
Patent: US2003/171377 A1, 2003 ;

66171-50-46-羟基烟酸甲酯

10561-91-81-甲基-6-氧代-1,6-二氢吡啶-3-羧酸乙酯

参考文献

Newkome, George R.; Kohli, Dalip K.; Kawato, Toshio
Journal of Organic Chemistry, 1980 , vol. 45, # 22 p. 4508 - 4511

66171-50-46-羟基烟酸甲酯

104941-01-7

参考文献

Ogata, Masaru; Matsumoto, Hiroshi; Kida, Shiro; Shimizu, Sumio; Tawara, Katsuya; Kawamura, Yoshimi
Journal of Medicinal Chemistry, 1987 , vol. 30, # 8 p. 1497 - 1502

66171-50-46-羟基烟酸甲酯

381247-99-02-羟基-3-溴-5-乙酸酯吡啶

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2009/106885 A1, 2009 ;
Location in patent: Page/Page column 296-297 ;
WO 2009/106885 A1

66171-50-46-羟基烟酸甲酯

56055-54-05,6-二氯烟酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
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