6-羟基烟酸甲酯合成路线

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

66171-50-46-羟基烟酸甲酯

365413-29-26-氯-5-碘烟酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

66171-50-46-羟基烟酸甲酯

1360952-35-76-氯-5-(三氟甲基)-3-吡啶羧酸甲酯+

78686-77-85-溴-6-氯烟酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

66171-50-46-羟基烟酸甲酯+

98-80-6苯硼酸

77837-09-36-氧代-1-苯基-1,6-二氢-吡啶-3-羧酸甲酯

参考文献

AUSPEX PHARMACEUTICALS, INC.; ZHANG, Chengzhi; SOMMERS, Andreas
Patent: WO2012/122165 A2, 2012 ;
Location in patent: Page/Page column 63 ;

66171-50-46-羟基烟酸甲酯

77837-08-26-氧代-1-苯基-1,6-二氢吡啶-3-甲酸

参考文献

AUSPEX PHARMACEUTICALS, INC.; ZHANG, Chengzhi; SOMMERS, Andreas
Patent: WO2012/122165 A2, 2012 ;

66171-50-46-羟基烟酸甲酯

694-85-91-甲基-2-吡啶酮

参考文献

Newkome, George R.; Kohli, Dalip K.; Kawato, Toshio
Journal of Organic Chemistry, 1980 , vol. 45, # 22 p. 4508 - 4511

66171-50-46-羟基烟酸甲酯

73781-91-66-氯烟酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

66171-50-46-羟基烟酸甲酯

73781-91-66-氯烟酸甲酯+

56055-54-05,6-二氯烟酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

66171-50-46-羟基烟酸甲酯

73781-91-66-氯烟酸甲酯+

1360952-35-76-氯-5-(三氟甲基)-3-吡啶羧酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

66171-50-46-羟基烟酸甲酯

109205-68-75-(羟甲基)吡啶-2(1H)-酮

参考文献

Dalhousie University
Patent: US2002/49330 A1, 2002 ;