3,3’-亚甲基双(5-甲基恶唑啉)合成路线 （共 2 条）
反应条件
in tetrahydrofuran
T=-78°C; 4 h;
参考文献
Salas-Coronado, Raul; Galvez-Ruiz, Juan Carlos; Guadarrama-Perez, Carlos; Flores-Parra, Angelina
Heterocycles, 2003 , vol. 60, # 5 p. 1123 - 1132
反应条件
1: 2-aminopropan-1-ol; paraformaldehyde Cooling with water-bath1/3 part of formaldehyde was added;
2: paraformaldehyde T=65°C; Second 1/3 part of formaldehyde was added;
3: paraformaldehyde T=140°C; third part of formaldehyde was added at 65 degree;CHeating up to 95 degree;C until disoslution of formaldehydeHeating / reflux;
参考文献
Baker Hughes Incorporated
Patent: US6339153 B1, 2002 ;
Location in patent: Page column 5 ;
