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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
66224-66-6
合成路线
（共 291 条）
66224-66-6
→
反应条件
6974-78-3
8-溴腺嘌呤
反应条件
water; bromine T=20°C;
参考文献
US2008/234297 A1, ;
Page/Page column 33; 38 ;
US 20080234297 A1
→
反应条件
73-40-5
鸟嘌呤
反应条件
NaH; ammonia in pyridine; water; benzoyl chloride; acetic acid; N,N-dimethyl-formamide
参考文献
Segev; David
Patent: US5908845 A1, 1999 ;
66224-66-6
+
52450-18-7
3’-氨基-2’,3’-双脱氧胸苷
→
反应条件
125944-11-8
反应条件
phosphate buffer; glutaraldehyde-treated cells of E.coli BM-11; Na-acetate buffer T=50°C; 24 h;
参考文献
Zaitseva; Kvasyuk; Vaaks; Barai; Bokut; Zinchenko; Mikhailopulo
Nucleosides and Nucleotides, 1994 , vol. 13, # 1-3 p. 819 - 834
22164-16-5
+
66224-66-6
→
反应条件
578-76-7
7-甲基鸟嘌呤
+
58-61-7
腺苷
反应条件
potassium dihydrogenphosphate; purine nucleoside phosphorylase in water T=60°C; 22 h; pH 7.0;
参考文献
Voegel; Altorfer; Benner
Helvetica Chimica Acta, 1993 , vol. 76, # 5 p. 2061 - 2069
66224-66-6
→
反应条件
578-76-7
7-甲基鸟嘌呤
+
958-09-8
2’-脱氧腺苷
反应条件
potassium dihydrogenphosphate; purine nucleoside phosphatase in water T=45°C; 16 h; enzymatic synthesis of various β-D-ribo (and desoxyribo) nucleoside analogs; effect of temperature: 25-60 deg C;
参考文献
Voegel; Altorfer; Benner
Helvetica Chimica Acta, 1993 , vol. 76, # 5 p. 2061 - 2069
66224-66-6
+
56287-17-3
→
反应条件
20187-82-0
反应条件
in water T=37°C; 408 h; thymidine phosphorylase, purine nucleoside phosphorylase, phosphate buffer, pH 7;
参考文献
Tuttle; Tisdale; Krenitsky
Journal of Medicinal Chemistry, 1993 , vol. 36, # 1 p. 119 - 125
3083-77-0
+
66224-66-6
→
反应条件
5536-17-4
反应条件
phosphate buffer; cell paste of Enterobacter aerogenes AJ 11125 T=60°C; 15 h; pH 7.0; several purine bases also investigated;
参考文献
Utagawa; Morisawa; Yamanaka; et al.
Agricultural and Biological Chemistry, 1985 , vol. 49, # 7 p. 2167 - 2171
108321-99-9
+
66224-66-6
→
反应条件
5536-17-4
反应条件
2-hydroxyethanethiol; manganese (II) chloride; purine nucleoside phosphorylase in various solvent(s) T=45°C; pH=7; 96 h;
参考文献
Taverna-Porro, Marisa; Bouvier, Leon A.; Pereira, Claudio A.; Montserrat, Javier M.; Iribarren, Adolfo M.
Tetrahedron Letters, 2008 , vol. 49, # 16 p. 2642 - 2645
→
反应条件
5536-17-4
反应条件
clostridium perfringen uridine phosphorylase; purine nucleoside phosphorylase from aeromonas hydrophila II in aq. phosphate buffer T=20°C; pH=7.5; Enzymatic reaction; Reagent/catalyst;
参考文献
Serra, Immacolata; Ubiali, Daniela; Piskur, Jure; Christoffersen, Stig; Lewkowicz, Elizabeth S.; Iribarren, Adolfo M.; Albertini, Alessandra M.; Terreni, Marco
ChemPlusChem, 2013 , vol. 78, # 2 p. 157 - 165
66224-66-6
+
13035-61-5
→
反应条件
906361-01-1
+
7387-57-7
反应条件
1: 6-aminopurine With ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane 2.5 h; Heating; 2: (2R,3R,4R,5S)-4,5-bis(acetyloxy)-2-[(acetyloxy)methyl]tetrahydro-3-furanyl acetate With trimethylsilyl trifluoromethanesulfonate in acetonitrile T=20°C; 1.33333 h;
参考文献
Tetrahedron, , vol. 62, # 43 p. 10123 - 10129
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