5-甲氧基-2,4-二羟基嘧啶合成路线 （共 5 条）
反应条件
1: With water; chloroacetic acid 2 h; Heating / reflux; 2: With hydrogenchloride; water 16 h; Heating / reflux;
参考文献
Johnson, Neil W.; Bryan, Deborah L.
Patent: US2008/182852 A1, 2008 ;
Location in patent: Page/Page column 15 ;
US 20080182852 A1
反应条件
1: methoxyacetic acid methyl ester; formic acid ethyl ester With sodium in toluene 2: urea in ethanol Reflux;
参考文献
Journal of Chemical and Engineering Data, , vol. 55, # 3 p. 1402 - 1404
参考文献
Chemical Research in Toxicology, , vol. 12, # 9 p. 802 - 808
反应条件
1: trichlorophosphate; N,N-dimethyl-aniline / 2 h / Reflux 2: zinc; water / ethanol / 4 h / Reflux View Scheme
参考文献
SENEXIS LIMITED; HORWELL, David Christopher; SCOPES, David Ian Carter
Patent: WO2011/144578 A1, 2011 ;
反应条件
pyridine; trichlorophosphate T=180°C; P=150.015 - 900.09 Torr; Neat (no solvent)Large scale reaction;
参考文献
Sun, Zhihua; Wang, Han; Wen, Kun; Li, Ya; Fan, Erkang
Journal of Organic Chemistry, 2011 , vol. 76, # 10 p. 4149 - 4153
