4-叔丁基-2-羟基苯甲醛合成路线 (共 6 条)
反应条件
1: With titanium tetrachloride in dichloromethane T=0 - 20°C; 1 h; 2: With water in dichloromethane T=0°C;
参考文献
ALLERGAN, INC.
Patent: WO2005/58798 A2, 2005 ;
Location in patent: Page/Page column 104 ;
反应条件
trifluoroacetic acid in water
参考文献
G.D. Searle and Co.
Patent: US6077850 A1, 2000 ;
反应条件
trifluoroacetic acid in water
参考文献
McKearn, John P.; Gordon, Gary B.; Cunningham, James; Gately, Stephen T.; Koki, Alane T.; Masferrer, Jaime L.
Patent: US2002/103141 A1, 2002 ;
反应条件
1: in acetic acid T=130°C; 3 h; 2: With hydrogenchloride 3: T=130°C; 0.166667 h;
参考文献
WO2004/783 A1, ;
Page 20 ;
反应条件
1: 3-t-butylphenol With ethylmagnesium bromide in diethyl ether T=20°C; 16 h; 2: formaldehyd With N,N,N',N',N'',N''-hexamethylphosphoric triamide in benzene Heating;
参考文献
Tyman, John H.P.; Mehet, Satinderjit K.
Chemistry and Physics of Lipids, 2003 , vol. 126, # 2 p. 177 - 199