pyridine in dichloromethane T=20°C; Sealed tubeInert atmosphere;

1: boron trifluoride diethyl etherate / xylenes / 6 h / 180 °C 2: pyridine / dichloromethane / 24 h / 20 °C View Scheme

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 70 °C 2: boron trifluoride diethyl etherate / xylenes / 6 h / 180 °C 3: pyridine / dichloromethane / 24 h / 20 °C View Scheme

perfluorodecahydronaphthalene in hexane; toluene 1 h; Heating;

manganese(IV) oxide; copper(II) bis(trifluoromethanesulfonate); potassium carbonate; (R,R)-Ph-BOX in α,α,α-trifluorotoluene T=120°C; 24 h; Molecular sieveInert atmosphereSealed tube; optical yield given as percent eeenantioselective reaction;