1: 4-bromophenylacetic acid in tetrahydrofuran; hexane T=-78°C; 1 h; 2: vinyl-dimethyl-chlorosilane in tetrahydrofuran; hexane T=-78°C; 12 h; 3: With hydrogenchloride; water in tetrahydrofuran; hexane; ethyl acetate

1: 1.) Mg, I2 / 1.) THF, reflux, 5.5 h, 2.) THF, 4 deg C to room temperature, overnight; reflux, 1 h 2: acetonitrile / 48 h / 120 °C 3: aq. NaOH / 24 h / Ambient temperature View Scheme

1: acetonitrile / 48 h / 120 °C 2: aq. NaOH / 24 h / Ambient temperature View Scheme