2-[(3-甲氧基-3-氧代丙基)硫代]丙酸乙酯合成路线 （共 4 条）
反应条件
sodium hydride in tetrahydrofuran; mineral oil
T=20°C;
参考文献
CELLZOME LIMITED; LYNCH, Rosemary; CANSFIELD, Andrew David; HARDY, Daniel Paul; FEUTRILL, John Thomas; ADREGO, Rita; ELLARD, Katie; LADDUWAHETTY, Tammy
Patent: WO2013/50508 A1, 2013 ;
Location in patent: Page/Page column 45; 70 ;
反应条件
ethanol; sodium
1.) 20 deg C, 1 h; 3.) reflux, 2 h;
参考文献
Mosandl, Armin; Hener, Uwe; Fenske, Heinz-Dieter
Liebigs Annalen der Chemie, 1989 , p. 859 - 862
反应条件
sodium in methanol
2 h; Ambient temperature;
参考文献
Henderson, Scott A.; O'Connor, Jacqueline; Rendina, Alan R.; Savage, G. Paul; Simpson, Gregory W.
Australian Journal of Chemistry, 1995 , vol. 48, # 12 p. 1907 - 1916
反应条件
1: 70 percent / Na / methanol / 2 h / Ambient temperature
2: 48 percent / 1.) HONH2*HCl, 2.) satd. NaHCO3 / acetonitrile / 3 h / Heating
View Scheme
参考文献
Henderson, Scott A.; O'Connor, Jacqueline; Rendina, Alan R.; Savage, G. Paul; Simpson, Gregory W.
Australian Journal of Chemistry, 1995 , vol. 48, # 12 p. 1907 - 1916
