3'-氨基-2',3'-双脱氧鸟苷合成路线 （共 3 条）
反应条件
phosphate buffer; cells of E.coli BMT-38; Na-acetate buffer T=50°C; 28 h;
参考文献
Zaitseva; Kvasyuk; Vaaks; Barai; Bokut; Zinchenko; Mikhailopulo
Nucleosides and Nucleotides, 1994 , vol. 13, # 1-3 p. 819 - 834
反应条件
1: 1.) lithium azide, 2.) aq. acetic acid / 1.) DMF, 150 deg C, 3 h, 2.) 55 deg C, 4 h 2: 78 percent / Ph3P, pyridine, aq. NH3 3: 20.5 percent / cells of E.coli BMT-38, Na-acetate buffer, phosphate buffer, pH 6.75 / 28 h / 50 °C View Scheme
参考文献
Nucleosides and Nucleotides, , vol. 13, # 1-3 p. 819 - 834
反应条件
1: 78 percent / Ph3P, pyridine, aq. NH3 2: 20.5 percent / cells of E.coli BMT-38, Na-acetate buffer, phosphate buffer, pH 6.75 / 28 h / 50 °C View Scheme
参考文献
Nucleosides and Nucleotides, , vol. 13, # 1-3 p. 819 - 834
