4-碘-2,6-二硝基甲苯合成路线 （共 7 条）
反应条件
TICA
T=70°C; 17 h; Darkness; regioselective reaction;
参考文献
Da Ribeiro, Rodrigo S.; Esteves, Pierre M.; De Mattos, Marcio C. S.
Synthesis, 2011 , # 5 p. 739 - 744
反应条件
1: dioxane; sulfur hydrogen; water; ammonia
2: Diazotization.Behandlung der Diazoniumsalz-Loesung mit KI
View Scheme
参考文献
Parkes; Farthing
Journal of the Chemical Society, 1948 , p. 1275,1277
反应条件
Diazotization.Behandlung der Diazoniumsalz-Loesung mit KI;
参考文献
Parkes; Farthing
Journal of the Chemical Society, 1948 , p. 1275,1277
反应条件
1: H2S, aq. NH3 / dioxane
2: (i) NaNO2, H3PO4, H2SO4, (ii) KI
3: Sn, aq. HCl
4: (i) NaNO2, H3PO4, H2SO4, (ii) KI
View Scheme
参考文献
Arotsky,J. et al.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 1480 - 1485
反应条件
ammonium hydroxide; hydrogen sulfide in 1,4-dioxane
参考文献
GLENMARK PHARMACEUTICALS S.A.
Patent: WO2008/110863 A1, 2008 ;
Location in patent: Page/Page column 29 ;
WO 2008/110863 A1
反应条件
hydrogen iodide
T=110°C; 16 h;
参考文献
Camerel, Franck; Ulrich, Gilles; Ziessel, Raymond
Organic Letters, 2004 , vol. 6, # 23 p. 4171 - 4174
反应条件
sodium dichromate; sulfuric acid
参考文献
Segura, Pascual; Bunnett, Joseph F.; Villanova, Laura
Journal of Organic Chemistry, 1985 , vol. 50, # 7 p. 1041 - 1045
