6-氯-2-苯基喹啉-4-甲酸合成路线 （共 5 条）
反应条件
potassium hydroxide in ethanol; water T=80 - 90°C; Pfitzinger Quinoline Synthesis;
参考文献
Islam, Rafiqul; Hossain, Md. Imran; Okamoto, Yoshinari; Nagamatsu, Tomohisa; Anraku, Kensaku; Okawara, Tadashi
Heterocycles, 2014 , vol. 89, # 3 p. 693 - 708
反应条件
[Yb(PFO)3] in water Doebner reaction; 3 h; Reflux;
参考文献
Wang, Li-Min; Hu, Liang; Chen, Hong-Juan; Sui, Yuan-Yuan; Shen, Wei
Journal of Fluorine Chemistry, 2009 , vol. 130, # 4 p. 406 - 409
反应条件
1: sodium sulfate; hydrogenchloride; hydroxylamine hydrochloride / water / 2.5 h / 85 °C 2: sulfuric acid / 60 - 90 °C 3: potassium hydroxide / ethanol / 72.5 h / |Reflux View Scheme
参考文献
Letters in Drug Design and Discovery, , vol. 10, # 5 p. 420 - 426
反应条件
1: sulfuric acid / 60 - 90 °C 2: potassium hydroxide / ethanol / 72.5 h / |Reflux View Scheme
参考文献
Letters in Drug Design and Discovery, , vol. 10, # 5 p. 420 - 426
反应条件
Auf Temperaturen oberhalb des Schmelzpunkts unter vermindertem Druck;
参考文献
Buu-Hoi et al.
Journal of Organic Chemistry, 1953 , vol. 18, p. 1209,1219
