3,4,5-三乙酸基苯甲酸合成路线 （共 14 条）
参考文献
Schiff
Justus Liebigs Annalen der Chemie, 1872 , vol. 163, p. 218
Chemische Berichte, 1879 , vol. 12, p. 1533
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Sisley
Bulletin de la Societe Chimique de France, 1894 , vol. <3> 11, p. 565
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Boettinger
Chemische Berichte, 1884 , vol. 17, p. 1503
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Nachbaur
Jahresbericht ueber die Fortschritte der Chemie und Verwandter Theile Anderer Wissenschaften, 1857 , p. 312
反应条件
thionyl chloride
0.333333 h; Heating;
参考文献
Ye, Junju; Abiman, Poobalasingam; Crossley, Alison; Jones, John H.; Wildgoose, Gregory G.; Compton, Richard G.
Langmuir, 2010 , vol. 26, # 3 p. 1776 - 1785
反应条件
1: 72 percent / BH3*Me2S / tetrahydrofuran / 20 °C
2: 70 percent / (COCl)2; DMSO; Et3N / CH2Cl2 / -78 - 20 °C
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参考文献
Rosenmund; Zetzsche
Chemische Berichte, 1918 , vol. 51, p. 598
反应条件
1: 91 percent / thionyl chloride / 1 h / 85 °C
2: 81 percent / CHCl3; diethyl ether / 0.5 h / -10 °C
3: 87 percent / hydrogen chloride / dioxane; diethyl ether / 0.5 h / 10 °C
4: 75 percent / acetic acid; potassium acetate; H2SO4 / 3 h / 100 °C
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参考文献
Kraus, Michael; Biskup, Ellen; Richling, Elke; Schreier, Peter
Journal of Labelled Compounds and Radiopharmaceuticals, 2006 , vol. 49, # 13 p. 1151 - 1162
