6-甲基-2-苯基-1H-吲哚合成路线 （共 11 条）
反应条件
5 Au/Fe2O3; hydrogen in toluene
T=60 - 120°C; P=750.075 - 15001.5 Torr; 2 h; Autoclave; chemoselective reaction;
参考文献
Yamane, Yoshihiro; Liu, Xiaohao; Hamasaki, Akiyuki; Ishida, Tamao; Haruta, Masatake; Yokoyama, Takushi; Tokunaga, Makoto
Organic Letters, 2009 , vol. 11, # 22 p. 5162 - 5165
反应条件
rhodium(II) heptafluorobutyrate in toluene
T=60°C; 16 h; Molecular sieve;
参考文献
Shen, Meihua; Leslie, Brooke E.; Driver, Tom G.
Angewandte Chemie - International Edition, 2008 , vol. 47, # 27 p. 5056 - 5059
反应条件
palladium dichloride in acetonitrile
T=60°C; Michael Addition; 24 h; Inert atmosphere;
参考文献
Janreddy, Donala; Kavala, Veerababurao; Kuo, Chun-Wei; Kuo, Ting-Shen; He, Chiu-Hui; Yao, Ching-Fa
Tetrahedron, 2013 , vol. 69, # 15 p. 3323 - 3330
反应条件
zinc dibromide in toluene
T=110°C; 6 h; Inert atmosphere;
参考文献
Wang, Huifeng; Li, Yaming; Jiang, Linlin; Zhang, Rong; Jin, Kun; Zhao, Defeng; Duan, Chunying
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 13 p. 4983 - 4986
反应条件
palladium diacetate; potassium carbonate in 1-methyl-pyrrolidin-2-one
T=140°C; 8 h; Sealed tubeInert atmosphere;
参考文献
Zhang, Jiajun; Meng, Ling-Guo; Li, Pinhua; Wang, Lei
RSC Advances, 2013 , vol. 3, # 19 p. 6807 - 6812
反应条件
potassium hydroxide; water
T=70°C; 1 h;
参考文献
Taylor, Edward C.; Katz, Alan H.; Salgado-Zamora, Hector
Tetrahedron Letters, 1985 , vol. 26, # 48 p. 5963 - 5966
反应条件
1: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in N,N-dimethyl acetamide
T=20°C; Sonogashira Cross-Coupling; 1 h;
2: With sodium hydroxide in N,N-dimethyl acetamide
T=140°C;
参考文献
Yu, Xufen; Park, Eun-Jung; Kondratyuk, Tamara P.; Pezzuto, John M.; Sun, Dianqing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 44 p. 8835 - 8847
反应条件
1: 95 percent / palladium(II) chloride / acetonitrile / 3 h / Heating
2: 80 percent / 2 N alcoholic potassium hydroxide, one drop of water / 1 h / 70 °C
View Scheme
参考文献
Taylor, Edward C.; Katz, Alan H.; Salgado-Zamora, Hector
Tetrahedron Letters, 1985 , vol. 26, # 48 p. 5963 - 5966
反应条件
1: silver(l) oxide / dimethyl sulfoxide / 12 h / 130 °C / |Sealed tube; |Inert atmosphere
2: potassium carbonate; palladium diacetate / 1-methyl-pyrrolidin-2-one / 8 h / 140 °C / |Sealed tube; |Inert atmosphere
View Scheme
参考文献
Zhang, Jiajun; Meng, Ling-Guo; Li, Pinhua; Wang, Lei
RSC Advances, 2013 , vol. 3, # 19 p. 6807 - 6812
反应条件
1: acetic acid / ethanol / 100 °C
2: 1-propanephosphonic acid cyclic anhydride / toluene / 120 °C
View Scheme
参考文献
Lian, Xiao-Li; Lei, Hao; Quan, Xue-Jing; Ren, Zhi-Hui; Wang, Yao-Yu; Guan, Zheng-Hui
Chemical Communications, 2013 , vol. 49, # 74 p. 8196 - 8198
