6-硝基-N-[2-[4-(戊氧基)苯基]乙基]-4-喹唑啉胺合成路线 （共 4 条）
反应条件
triethylamine in isopropyl alcohol
T=20°C;
参考文献
Tobe, Masanori; Isobe, Yoshiaki; Tomizawa, Hideyuki; Nagasaki, Takahiro; Takahashi, Hirotada; Hayashi, Hideya
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 18 p. 3869 - 3878
反应条件
1: thionyl chloride; N,N-dimethylformamide / 3 h / Heating
2: triethylamine / propan-2-ol / 20 °C
View Scheme
参考文献
Tobe, Masanori; Isobe, Yoshiaki; Tomizawa, Hideyuki; Nagasaki, Takahiro; Takahashi, Hirotada; Hayashi, Hideya
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 18 p. 3869 - 3878
反应条件
1: aq. HCl / 1 h
2: thionyl chloride; N,N-dimethylformamide / 3 h / Heating
3: triethylamine / propan-2-ol / 20 °C
View Scheme
参考文献
Tobe, Masanori; Isobe, Yoshiaki; Tomizawa, Hideyuki; Nagasaki, Takahiro; Takahashi, Hirotada; Hayashi, Hideya
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 18 p. 3869 - 3878
反应条件
1: aqueous ammonia; 1-ethyl-3-[(dimethylamino)propyl]carbodiimide; 1-hydroxybenzotriazole / dimethylformamide / 4 h
2: aq. HCl / 1 h
3: thionyl chloride; N,N-dimethylformamide / 3 h / Heating
4: triethylamine / propan-2-ol / 20 °C
View Scheme
参考文献
Tobe, Masanori; Isobe, Yoshiaki; Tomizawa, Hideyuki; Nagasaki, Takahiro; Takahashi, Hirotada; Hayashi, Hideya
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 18 p. 3869 - 3878
