sodium hydride in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; 2 h;

sodium hydride in N,N-dimethyl-formamide 17 h; Heating;

1: 4-methyl-N-(2-methyl-allyl)-benzenesulfonamide With sodium hydride in N,N-dimethyl-formamide T=0°C; Inert atmosphere; 2: but-3-en-1-yl methanesulfonate in N,N-dimethyl-formamide T=100°C; 12 h; Inert atmosphere;

potassium carbonate in acetonitrile Inert atmosphereReflux;

1: 36 percent / K2CO3 / acetone 2: 45 percent / NaH / dimethylformamide View Scheme