二甲羟胺盐酸盐合成路线

参考文献

Suzuki, Takayoshi; Nagano, Yuki; Matsuura, Azusa; Kohara, Arihiro; Ninomiya, Shin-Ichi; Kohda, Kohfuku; Miyata, Naoki
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 24 p. 4321 - 4326

653604-30-9

参考文献

Wendt, Michael D.; Rockway, Todd W.; Geyer, Andrew; McClellan, William; Weitzberg, Moshe; Zhao, Xumiao; Mantei, Robert; Nienaber, Vicki L.; Stewart, Kent; Klinghofer, Vered; Giranda, Vincent L.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 2 p. 303 - 324

669066-91-55-溴-3-氟吡啶-2-羧酸+

6638-79-5二甲羟胺盐酸盐

669066-92-6

参考文献

JERINI AG
Patent: WO2009/36996 A2, 2009 ;
Location in patent: Page/Page column 106 ;
WO 2009/036996 A2

6066-45-12-溴-2,3,3,3-四氟丙酰氯+

6638-79-5二甲羟胺盐酸盐

677353-90-1

参考文献

Sato, Kei; Sekiguchi, Takashi; Ishihara, Takashi; Konno, Tsutomu; Yamanaka, Hiroki
Journal of Organic Chemistry, 2004 , vol. 69, # 15 p. 5041 - 5047

6638-79-5二甲羟胺盐酸盐+

208173-19-72-氟-3-(三氟甲基)苄氧基氯

680610-54-2

参考文献

Beier, Christian; Benting, Jurgen; Christian, Isabelle; Coqueron, Pierre-Yves; Duboist, Christophe; Genix, Pierre; Grosjean-Cournoyer, Marie-Claire; Hartmann, Benoit; Hutin, Pierre; Portz, Daniela; Rinolfi, Philippe; Voerste, Arnd; Vors, Jean-Pierre; Wachendorff-Neumann, Ulrike
Patent: US2010/286173 A1, 2010 ;
Location in patent: Page/Page column 40 ;

115029-22-62-氟-3-(三氟甲基)苯甲酸+

6638-79-5二甲羟胺盐酸盐

680610-54-2

参考文献

Wyeth
Patent: WO2004/31159 A1, 2004 ;
Location in patent: Page 26-27 ;
WO 2004/031159 A1

680610-54-2

参考文献

Murray, Iain A.; Krishnegowda, Gowdahalli; Dinatale, Brett C.; Flaveny, Colin; Chiaro, Chris; Lin, Jyh-Ming; Sharma, Arun K.; Amin, Shantu; Perdew, Gary H.
Chemical Research in Toxicology, 2010 , vol. 23, # 5 p. 955 - 966

6638-79-5二甲羟胺盐酸盐+

161957-56-83-溴-2-氟苯甲酸

680610-73-5N-甲氧基-N-甲基-3-溴-2-氟苯甲酰胺

参考文献

Andreini, Matteo; Gabellieri, Emanuele; Guba, Wolfgang; Marconi, Guido; Narquizian, Robert; Power, Eoin; Travagli, Massimiliano; Woltering, Thomas; Wostl, Wolfgang
Patent: US2009/209529 A1, 2009 ;
Location in patent: Page/Page column 34 ;

680610-73-5N-甲氧基-N-甲基-3-溴-2-氟苯甲酰胺

参考文献

ASTRAZENECA AB; SCHERING AG
Patent: WO2007/46747 A1, 2007 ;
Location in patent: Page/Page column 66-67 ;
WO 2007/046747 A1

374554-41-33-溴-2-氟苯甲酰氯+

6638-79-5二甲羟胺盐酸盐

680610-73-5N-甲氧基-N-甲基-3-溴-2-氟苯甲酰胺

参考文献

Kishore Kumar; Chavarria, Gustavo E.; Charlton-Sevcik, Amanda K.; Arispe, Wara M.; MacDonough, Matthew T.; Strecker, Tracy E.; Chen, Shen-En; Siim, Bronwyn G.; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 4 p. 1415 - 1419