1: 2-phenoxyacetic acid With 1,1'-carbonyldiimidazole in dichloromethane; water
T=0 - 20°C; 0.5 h; Inert atmosphere;
2: O,N-dimethyl-hydroxylamine hydrochloride With triethylamine in dichloromethane; water
T=0 - 20°C; Inert atmosphere;
参考文献
NORTH CAROLINA STATE UNIVERSITY; LINDSEY, Jonathan S.; MASS, Olga
Patent: WO2013/62670 A2, 2013 ;
Location in patent: Page/Page column 79 ;
1: in chloroform
0.166667 h; Cooling with ice;
2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in chloroform
0.166667 h;
3: With triethylamine in chloroform
3.16667 h;
Duong, Hung A.; Gilligan, Ruth E.; Cooke, Michael L.; Phipps, Robert J.; Gaunt, Matthew J.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 2 p. 463 - 466