2,3-二氢-3-氧代-1,2-苯并异噻唑-2-乙酸甲酯1,1-二氧化物合成路线 (共 33 条)
反应条件
in methanol
T=20°C; 36 h; other time, temperature; Product distribution;
参考文献
Schapira, Celia B.; Perillo, Isabel A.; Lamdan, Samuel
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1281 - 1288
反应条件
1: 92 percent / methanol / 0.02 h / 20 °C
2: methanol / Heating
3: 70 percent / 40percent sodium hydroxide / H2O / 28 h / Ambient temperature
4: H2O / recrystallization
View Scheme
参考文献
Schapira, Celia B.; Perillo, Isabel A.; Lamdan, Samuel
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1281 - 1288
反应条件
hydrogenchloride
1 h; Heating;
参考文献
Soubh; Besch; Otto, Hans-Hartwig
Pharmazie, 2002 , vol. 57, # 6 p. 384 - 392