反应条件
1: 85 percent / p-TsOH / diethyl ether / 5 h / 0 - 3 °C
2: 1.) LiNH2 / 1.) THF, 1.5 h, 2.) 4 h
3: Dowex W-50 (H+ form) / methanol / 20 h
4: H2, 1,2-diaminoethane / P2-Ni / ethanol
5: 89 percent / PPh3, CBr4 / CH2Cl2 / 1.) from 0 deg C to 20 deg C, 1 h, 2) 20 deg C, 14 h
6: 1.) butyllithium, HMPA, 2.) HMPA / 1.) THF, hexane, -20 deg C, 1 h, 2.) RT, 4 h
7: Dowex W-50 (H+ form) / methanol / 16 h
View Scheme
参考文献
Hoskovec, Michal; Saman, David; Koutek, Bohumir
Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, # 9 p. 2270 - 2281
