8-氨基-2,3-二氢-苯并[1,4]二噁英-5-羧酸合成路线 （共 4 条）
反应条件
hydrogenchloride in water
参考文献
Societe D'Etudes Scientifiques et Industrielles de L'ile-de-France
Patent: US4186135 A1, 1980 ;
反应条件
1: bromine; acetic acid / 2 h / 120 °C 2: sulfuric acid; nitric acid / acetic acid / 1 h / 37 - 50 °C 3: sodium carbonate; palladium on activated charcoal; hydrogen / water / 50 °C / 30003 Torr / |Autoclave View Scheme
反应条件
1: sulfuric acid; nitric acid / acetic acid / 1 h / 37 - 50 °C 2: sodium carbonate; palladium on activated charcoal; hydrogen / water / 50 °C / 30003 Torr / |Autoclave View Scheme
反应条件
thionyl chloride in ethanol; water
参考文献
Sanofi-Synthelabo
Patent: US6248757 B1, 2001 ;
