4-硝基-1,8-萘醛酸酐合成路线 （共 25 条）
反应条件
hydrogen; palladium on activated charcoal
参考文献
Cheon, Kap-Soo; Kazmaier, Peter M.; Keum, Sam-Rok; Park, Kuk-Tae; Buncel, Erwin
Canadian Journal of Chemistry, 2004 , vol. 82, # 4 p. 551 - 566
反应条件
baker's yeast; D-glucose in phosphate buffer; ethanol T=30°C; pH=6.5; 3 h;
参考文献
Li, Feng; Cui, Jingnan; Qian, Xuhong; Zhang, Rong
Chemical Communications, 2004 , # 20 p. 2338 - 2339
反应条件
copper(II) sulfate; sodium nitrite in N,N-dimethyl-formamide T=28 - 30°C; 2 h;
参考文献
Ayyangar, N. R.; Joshi, S. V.; Lugade, A. G.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, p. 842 - 845
反应条件
1: 88 percent / pyridine / 1.5 h / 60 °C 2: 80 percent / Sn, conc. HCl / ethanol / 2 h / 100 °C 3: 64 percent / pyridine / 0.75 h / 80 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 34, # 10 p. 876 - 878
反应条件
1: With sodium hydroxide in water T=100°C; 0.0166667 h; microwave irradiation; 2: With mercury(II) diacetate in water T=200°C; Pesci reaction; 0.5 h; microwave irradiation; 3: With hydrogenchloride in water T=120°C; 0.25 h; microwave irradiation; Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 62, # 19 p. 4690 - 4697
反应条件
in N,N-dimethyl-formamide T=120°C; 4 h;
参考文献
Alexiou, Michael; Tyman, John; Wilson, Ian
Tetrahedron Letters, 1981 , vol. 22, # 24 p. 2303 - 2306
反应条件
in water T=120°C; Condensation; 3 h;
参考文献
Alexiou, Michael S.; Tyman, John H. P.
Journal of Chemical Research, Miniprint, 2000 , # 5 p. 632 - 652
反应条件
1: SnCl2; HCl 2: 0.08 g / dimethylformamide / 3 h / 20 °C 3: K2CO3 / acetone View Scheme
参考文献
Alexiou, Michael S.; Tyman, John H. P.
Journal of Chemical Research, Miniprint, 2000 , # 5 p. 632 - 652
反应条件
1: hydroxylamine hydrochloride, sodium acetate / H2O / 3 h / 80 °C
2: Na2CO3 / H2O / 1 h / Heating
3: NaOH / ethanol; H2O / 16 h / 25 °C
4: H2 / 5percent Pd/C / tetrahydrofuran / 16 h / 2068.6 Torr
5: 75 percent / DIEA / dimethylformamide / a) 105 deg C, 1.5 h, b) 85 deg C, 1.5 h
6: 59 percent / DIEA / dimethylformamide / 1.42 h / 75 °C
7: Lawesson's reagent / toluene
8: NaOH / tetrahydrofuran; ethanol
9: NH3 / methanol
View Scheme
参考文献
Varney, Michael D.; Marzoni, Gifford P.; Palmer, Cindy L.; Deal, Judith G.; Webber, Stephanie; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 663 - 676
反应条件
in 2-methoxy-ethanol
T=100°C; 3 h;
参考文献
Staneva, Desislava; Grabchev, Ivo; Betcheva, Rosica
Dyes and Pigments, 2013 , vol. 98, # 1 p. 64 - 70
