1-(2-甲氧基苯基)-2-甲基-丙-1-醇合成路线 （共 10 条）
反应条件
iso-propylmagnesium bromide in tetrahydrofuran
T=0°C; 1 h;
参考文献
Sankyo Agro Company, Limited
Patent: EP1426365 A1, 2004 ;
Location in patent: Page 294 ;
反应条件
chromium dichloride; lithium iodide; B12 in N,N-dimethyl-formamide
T=20°C; Barbier reaction; 16 h;
参考文献
Wessjohann, Ludger A.; Schmidt, Gisela; Schrekker, Henri S.
Tetrahedron, 2008 , vol. 64, # 9 p. 2134 - 2142
反应条件
1: isopropyl bromide With iodine; magnesium in diethyl ether
0.5 h; Heating;
2: ortho-anisaldehyde in diethyl ether
2 h;
参考文献
Patel, Sabita; Panda, Mamata P.; Kuanar, Minati; Mishra
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 6 p. 1299 - 1301
反应条件
1: in tetrahydrofuran
T=0°C; 1 h; Inert atmosphere;
2: With water in tetrahydrofuran
T=20°C; 12 h; Inert atmosphere;
参考文献
Niyomura, Osamu; Nakaiida, Shoho; Yamada, Ryo; Kato, Shinzi; Ishida, Masaru; Ebihara, Masahiro; Ando, Fumio; Koketsu, Jugo
Molecules, 2009 , vol. 14, # 7 p. 2555 - 2572
反应条件
1-(2-methoxyphenyl)-2-methylpropan-1-one; trimethylaluminum; tri-n-butyl-tin hydride
1.) toluene, from -78 deg C to -40 deg C, 10 min, 2.) toluene; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ooi; Uraguchi; Kagoshima; Maruoka
Journal of the American Chemical Society, 1998 , vol. 120, # 21 p. 5327 - 5328
反应条件
4'-methoxyisobutyrophenone; trimethylaluminum; tri-n-butyl-tin hydride
1.) toluene, from -78 deg C to -40 deg C, 10 min, 2.) toluene; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ooi; Uraguchi; Kagoshima; Maruoka
Journal of the American Chemical Society, 1998 , vol. 120, # 21 p. 5327 - 5328
参考文献
Levy; Pernot
Bulletin de la Societe Chimique de France, 1931 , vol. <4> 49, p. 1730,1733
Full Text Show Details
Dutton et al.
Canadian Journal of Chemistry, 1953 , vol. 31, p. 1138,1140
参考文献
Yamashita,A. et al.
Bulletin of the Chemical Society of Japan, 1974 , vol. 47, p. 2508 - 2510
反应条件
1: aqueous H2SO4
2: Raney nickel; ethanol / Hydrogenation
View Scheme
参考文献
Dutton et al.
Canadian Journal of Chemistry, 1953 , vol. 31, p. 1138,1140
反应条件
with H2SO4 impregnated pumice stone
参考文献
Dutton et al.
Canadian Journal of Chemistry, 1953 , vol. 31, p. 1138,1140
