3-羟基-2-异丙氧基苯甲醛合成路线 (共 3 条)
反应条件
1: 2,3-dihydroxy-benzaldehyde With acetic anhydride; acetic acid
12 h; Heating;
2: isopropyl bromide With potassium carbonate in N,N-dimethyl-formamide
T=50°C; 12 h;
3: With sodium methylate in methanol; N,N-dimethyl-formamide
参考文献
Fischer, Dirk; Blechert, Siegfried
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 10 p. 1329 - 1332
反应条件
1: With methanol; sodium methylate
2: With water; acetic acid
参考文献
Blechert, Siegfried; Connon, Stephen
Patent: US2008/139861 A1, 2008 ;
Location in patent: Page/Page column 7 ;
反应条件
1: 2,3-dihydroxy-benzaldehyde With potassium carbonate in N,N-dimethyl-formamide
T=20°C; 1 h;
2: 2-iodo-propane in N,N-dimethyl-formamide
T=20°C; 20 h;
参考文献
Lebeuf, Raphael; Dunet, Julie; Beniazza, Redouane; Ibrahim, Dawood; Bose, Gopal; Berlande, Muriel; Robert, Frederic; Landais, Yannick
Journal of Organic Chemistry, 2009 , vol. 74, # 17 p. 6469 - 6478