2-{[(2E)-3,7,11,15-四甲基-2-十六碳烯-1-基]氧基}四氢-2H-吡喃合成路线 （共 12 条）
反应条件
2: KOH / methanol; hexane; H2O / 2 h / Ambient temperature View Scheme
参考文献
Schmid; Gerber; Hirth
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 684 - 702
反应条件
pyridinium p-toluenesulfonate in ethanol T=55°C; 1.5 h;
参考文献
Schmid; Gerber; Hirth
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 684 - 702
反应条件
magnesium; dilithium tetrachlorocuprate in tetrahydrofuran
10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.;
参考文献
Schmid; Gerber; Hirth
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 684 - 702
反应条件
dilithium tetrachlorocuprate in tetrahydrofuran
T=0°C; 2 h;
参考文献
Schmid; Gerber; Hirth
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 684 - 702
反应条件
1: POCl3 / 0.5 h
2: dimethylformamide / 3 h / 80 °C
3: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
View Scheme
参考文献
Schmid; Gerber; Hirth
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 684 - 702
反应条件
1: 73 percent / Ba(OH)2 / methanol
2: POCl3 / 0.5 h
3: dimethylformamide / 3 h / 80 °C
4: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
View Scheme
参考文献
Schmid; Gerber; Hirth
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 684 - 702
反应条件
1: POCl3 / 0.5 h
2: dimethylformamide / 3 h / 80 °C
3: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
View Scheme
参考文献
Schmid; Gerber; Hirth
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 684 - 702
反应条件
1: dimethylformamide / 3 h / 80 °C
2: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
View Scheme
参考文献
Schmid; Gerber; Hirth
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 684 - 702
反应条件
magnesium; copper(l) iodide in tetrahydrofuran
参考文献
Schmid; Gerber; Hirth
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 684 - 702
反应条件
magnesium; copper(l) chloride in tetrahydrofuran
参考文献
Schmid; Gerber; Hirth
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 684 - 702
