(1-苄基-1H-苯并咪唑-2-基)甲醇合成路线 （共 9 条）
反应条件
sodium hydroxide in methanol
T=20°C; 0.5 h;
参考文献
Dubey; Reddy, P.V.V. Prasada; Srinivas
Synthetic Communications, 2007 , vol. 37, # 10 p. 1675 - 1681
反应条件
sulfuric acid; silver nitrate in methanol; water
3 h; Heating;
参考文献
Khristich, B.I.; Tsupak, E.B.; Kononogova, O.I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 12 p. 1299 - 1302
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 12 p. 1679 - 1681
反应条件
1: o-nitro-N-benzylaminobenzene With hydrogenchloride; indium in water
T=100°C; 0.5 h;
2: hydroxyacetaldehyde in water
T=100°C; 0.5 h;
参考文献
Kommi, Damodara N.; Kumar, Dinesh; Bansal, Rohit; Chebolu, Rajesh; Chakraborti, Asit K.
Green Chemistry, 2012 , vol. 14, # 12 p. 3329 - 3335
反应条件
1: 2 h / 125 - 130 °C
2: water / Heating
3: 69 percent / TEBAC; K2CO3 / acetonitrile / 20 °C
4: 75 percent / aq. NaOH / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Dubey; Reddy, P.V.V. Prasada; Srinivas
Synthetic Communications, 2007 , vol. 37, # 10 p. 1675 - 1681
反应条件
1: 69 percent / TEBAC; K2CO3 / acetonitrile / 20 °C
2: 75 percent / aq. NaOH / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Dubey; Reddy, P.V.V. Prasada; Srinivas
Synthetic Communications, 2007 , vol. 37, # 10 p. 1675 - 1681
反应条件
1: water / Heating
2: 69 percent / TEBAC; K2CO3 / acetonitrile / 20 °C
3: 75 percent / aq. NaOH / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Dubey; Reddy, P.V.V. Prasada; Srinivas
Synthetic Communications, 2007 , vol. 37, # 10 p. 1675 - 1681
反应条件
1.1: water / 1.5 h / 100 °C
2.1: indium; hydrogenchloride / water / 0.5 h / 100 °C
2.2: 0.5 h / 100 °C
View Scheme
参考文献
Kommi, Damodara N.; Kumar, Dinesh; Bansal, Rohit; Chebolu, Rajesh; Chakraborti, Asit K.
Green Chemistry, 2012 , vol. 14, # 12 p. 3329 - 3335
反应条件
1.1: water / 1.5 h / 100 °C
2.1: indium; hydrogenchloride / water / 0.5 h / 100 °C
2.2: 0.5 h / 100 °C
View Scheme
参考文献
Kommi, Damodara N.; Kumar, Dinesh; Bansal, Rohit; Chebolu, Rajesh; Chakraborti, Asit K.
Green Chemistry, 2012 , vol. 14, # 12 p. 3329 - 3335
反应条件
thionyl chloride in chloroform
T=20°C; 18 h;
参考文献
MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.; WALDMANN, Herbert; TRIOLA, Gemma; WITTINGHOFER, Alfred; BASTIAENS, Philippe; VARTAK, Nachiket; PAPKE, Björn; ZIMMERMANN, Gunther; SHEHAB, Ismail; SCHULTZ-FADEMRECHT, Carsten; KOCH, Uwe
Patent: WO2014/27053 A1, 2014 ;
Location in patent: Page/Page column 111-112 ;
