1: 2-methylpropanoic acid methyl ester With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-78°C; 1.5 h; Inert atmosphere; 2: prenyl bromide in tetrahydrofuran; hexane T=-78°C; 1.5 h; Inert atmosphere;

sodium chloride; lithium diisopropyl amide in tetrahydrofuran; hexane; dimethyl sulfoxide

1: 2-methylpropanoic acid methyl ester With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=0 - 20°C; 0.5 h; Inert atmosphere; 2: 1-chloro-3-methyl-2-butene in tetrahydrofuran; hexane T=0 - 20°C; 24 h;

anhydrous magnesium perchlorate in dichloromethane 4 h; Ambient temperature; Yield given. Yields of byproduct given;