N-BOC-4-氨基苯甲酸合成路线 (共 21 条)
反应条件
triethylamine in 1,4-dioxane; water T=20°C; 24 h;
参考文献
Mu; Coffing; Riese II; Geahlen; Verdier-Pinard; Hamel; Johnson; Cushman
Journal of Medicinal Chemistry, 2001 , vol. 44, # 3 p. 441 - 452
反应条件
4-MeO-dppp; cesium fluoride; [Rh(OH)(cycloocta-1,5-diene)]2 in 1,4-dioxane T=60°C;
参考文献
Ukai, Kazutoshi; Aoki, Masao; Takaya, Jun; Iwasawa, Nobuharu
Journal of the American Chemical Society, 2006 , vol. 128, # 27 p. 8706 - 8707
反应条件
1: With lithium hydroxide; water in tetrahydrofuran; methanol T=20°C; 16 h; 2: With hydrogenchloride in water
参考文献
Eli Lilly and Company
Patent: US6639107 B1, 2003 ;
Location in patent: Page/Page column 36 ;
反应条件
polymethylhydrosiloxane; palladium on activated charcoal in ethanol T=20°C; Carboxylation; 3 h;
参考文献
Chandrasekhar; Chandraiah; Raji Reddy; Venkat Reddy
Chemistry Letters, 2000 , # 7 p. 780 - 781
反应条件
polymethylhydrosiloxane; palladium on activated charcoal in ethanol T=20°C; Carboxylation; 3 h;
参考文献
Chandrasekhar; Chandraiah; Raji Reddy; Venkat Reddy
Chemistry Letters, 2000 , # 7 p. 780 - 781
反应条件
anhydrous potassium trimethylsilanolate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; bis(dibenzylideneacetone)-palladium(0) in toluene T=40°C; 0.333333 h;
参考文献
Friis, Stig D.; Andersen, Thomas L.; Skrydstrup, Troels
Organic Letters, 2013 , vol. 15, # 6 p. 1378 - 1381
反应条件
sodium hydroxide in tetrahydrofuran; water T=20°C; 4 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 63, p. 231 - 238
反应条件
1: DMAP / tetrahydrofuran / Heating 2: K2CO3 / methanol / Heating View Scheme
参考文献
Synthetic Communications, , vol. 31, # 21 p. 3273 - 3280
反应条件
sodium hydroxide; citric acid in ethanol; water; ethyl acetate; N,N-dimethyl-formamide
反应条件
hydrogenchloride in t-butyl alcohol (t-BuOH)