3-羟基-2-甲氧苯甲醛合成路线 （共 10 条）
反应条件
palladium 10 on activated carbon; hydrogen in ethanol T=20°C; P=2327.23 Torr; 8 h;
参考文献
Chittimalla, Santhosh Kumar; Bandi, Chennakesavulu; Putturu, Sireesha; Kuppusamy, Rajesh; Boellaard, Kevin Christopher; Tan, David Chu Aan; Lum, Demi Ming Jie
European Journal of Organic Chemistry, 2014 , vol. 2014, # 12 p. 2565 - 2575
反应条件
hydrogen bromide in acetic acid Heating;
参考文献
Kemp,D.S. et al.
Tetrahedron, 1974 , vol. 30, p. 3969 - 3980
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=25°C; 20 h;
参考文献
Boger, Dale L.; Hong, Jiyong; Hikota, Masataka; Ishida, Michio
Journal of the American Chemical Society, 1999 , vol. 121, # 11 p. 2471 - 2477
反应条件
1: 2,3-dihydroxy-benzaldehyde With sodium hydride in dimethyl sulfoxide
T=20°C; 1 h;
2: methyl iodide in dimethyl sulfoxide
T=20°C; 20 h;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1591120 A1, 2005 ;
Location in patent: Page/Page column 89 ;
EP 1591120 A1
反应条件
1: With sodium hydride in dimethyl sulfoxide
T=20°C; 1 h;
2: With methyl iodide
T=20°C; 18 h;
参考文献
Assens, Jean-Louis; Bernhart, Claude; Cabanel-Haudricourt, Frederique; Gautier, Patrick; Nisato, Dino
Patent: US2003/225100 A1, 2003 ;
Location in patent: Page 20 ;
反应条件
1: 2,3-dihydroxy-benzaldehyde With potassium hydrogencarbonate in N,N-dimethyl-formamide
0.5 h; Inert atmosphere;
2: methyl iodide in N,N-dimethyl-formamide
T=20°C; 28 h; Inert atmosphere;
参考文献
Lowell, Andrew N.; Wall, Philip D.; Waters, Stephen P.; Kozlowski, Marisa C.
Tetrahedron, 2010 , vol. 66, # 30 p. 5573 - 5582
反应条件
boron trichloride in dichloromethane
1 h; Ambient temperature;
参考文献
Banwell; Flynn; Stewart
Journal of Organic Chemistry, 1998 , vol. 63, # 24 p. 9139 - 9144
反应条件
aluminium trichloride in dichloromethane
3 h; Ambient temperature;
参考文献
Banwell; Flynn; Stewart
Journal of Organic Chemistry, 1998 , vol. 63, # 24 p. 9139 - 9144
参考文献
Funke; Gombert
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1959 , vol. 246, p. 2084
反应条件
1: HBr / acetic acid / Heating
2: o-hydroxylammonium sulfonate, EtOAc / H2O
View Scheme
参考文献
Kemp,D.S. et al.
Tetrahedron, 1974 , vol. 30, p. 3969 - 3980
