3-碘-1-t甲苯磺酰-1H-吡咯并[2,3-b]吡啶合成路线 （共 2 条）
反应条件
1: With n-butyllithium in tetrahydrofuran T=-78°C; 0.5 h; 2: With tri-isopropoxy-borane in tetrahydrofuran T=-78°C; 1 h;
参考文献
CELLTECH R and D LIMITED
Patent: WO2006/38001 A1, 2006 ;
Location in patent: Page/Page column 39 ;
WO 2006/038001 A1
反应条件
tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide in dichloromethane
T=20°C; 0.5 h; Inert atmosphereReflux;
参考文献
Huang, Richard Y.; Franke, Patrick T.; Nicolaus, Norman; Lautens, Mark
Tetrahedron, 2013 , vol. 69, # 22 p. 4395 - 4402
