1-异丙基-2,3,4,9-四氢-1H-beta-咔啉合成路线 (共 4 条)
反应条件
T=80°C; Pictet-Spengler Synthesis; 2 h; Green chemistry;
参考文献
Handy, Scott; Wright, Matthew
Tetrahedron Letters, 2014 , vol. 55, # 23 p. 3440 - 3442
反应条件
(R)-TRIP-BINOL; C89H110IrN2O6PS; hydrogen in toluene
T=20°C; P=15001.5 Torr; 15 h;
参考文献
Li, Chaoqun; Wang, Chao; Villa-Marcos, Barbara; Xiao, Jianliang
Journal of the American Chemical Society, 2008 , vol. 130, # 44 p. 14450 - 14451
反应条件
sulfuric acid
T=50°C; Pictet-Spengler reaction; 48 h;
参考文献
Voskressensky; Borisova; Kulikova; Dolgova; Kleimenov; Sorokina; Titov; Varlamov
Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 5 p. 587 - 598
反应条件
in ethanol
Pictet-Spengler cyclisation; 20 h; Inert atmosphereReflux;
参考文献
Dong, Jing; Shi, Xiao-Xin; Yan, Jing-Jing; Xing, Jing; Zhang, Qiang; Xiao, Sen
European Journal of Organic Chemistry, 2010 , # 36 p. 6987 - 6992