(1R,2S)-1-(4-甲基苯基)-1,2-环丙烷二甲酸合成路线 （共 2 条）
反应条件
1: 70 percent / urea / xylene / Heating 2: 58 percent / sodium bis(2-methoxyethoxy)aluminum hydride / benzene / 2 h / Heating View Scheme
参考文献
Epstein, Joseph W.; Brabander, Herbert J.; Fanshawe, William J.; Hofmann, Corris M.; McKenzie, Thomas C.; et al.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 5 p. 481 - 490
反应条件
1: 70 percent / urea / xylene / Heating
2: 58 percent / sodium bis(2-methoxyethoxy)aluminum hydride / benzene / 2 h / Heating
3: 44 percent / HCOOH / 3 h / 100 °C
View Scheme
参考文献
Epstein, Joseph W.; Brabander, Herbert J.; Fanshawe, William J.; Hofmann, Corris M.; McKenzie, Thomas C.; et al.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 5 p. 481 - 490
