1-(三甲基硅氧烷)环己烯合成路线 （共 370 条）
反应条件
boron trifluoride diethyl etherate in dichloromethane
other reagent (LiF), other temperature, other time; MechanismProduct distribution;
参考文献
Kashin, A. N.; Tul'chinskii, M. L.; Bumagin, N. A.; Beletskaya, I. P.; Reutov, O. A.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, # 8 p. 1390 - 1395
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 8 p. 1588 - 1595
反应条件
1: With triethylamine in hexane
T=20°C; Inert atmosphere;
2: With toluene-4-sulfonic acid in hexane
T=70°C; Inert atmosphere; regioselective reaction;
参考文献
Schmitt, Daniel C.; Lam, Leighann; Johnson, Jeffrey S.
Organic Letters, 2011 , vol. 13, # 19 p. 5136 - 5139
反应条件
1: With (S)-B-3,5-bis(trifluoromethyl)phenyloxazoborolidine
T=-78°C; Condensation; Mukaiyama aldol reaction; 17 h;
2: With hydrogenchloride; water in tetrahydrofuran
T=20°C; Hydrolysis; Title compound not separated from byproducts;
参考文献
Ishihara; Kondo; Yamamoto
Journal of Organic Chemistry, 2000 , vol. 65, # 26 p. 9125 - 9128
反应条件
hydrogenchloride; water; lt;Pd((R)-p-tol-binap)(H2O)2gt;lt;BF4gt;2
1) DMF, 20 deg C, 43 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Li, Hui-Jing; Tian, Hong-Yu; Wu, Yan-Chao; Chen, Yong-Jun; Liu, Li; Wang, Dong; Li, Chao-Jun
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 9 p. 1247 - 1256
反应条件
(2R,2'R)-dimethyl 2,2'-(1,7-dioxa-4,10-diazacyclododecane-4,10-diyl)dipropanoate; Eu(trifluoromethanesulfonate)3 in ethanol; water
T=-25°C; Mukaiyama reaction; 168 h; optical yield given as percent eestereoselective reaction;
参考文献
Mei, Yujiang; Averill, Derek J.; Allen, Matthew J.
Journal of Organic Chemistry, 2012 , vol. 77, # 13 p. 5624 - 5632
反应条件
titanium tetrachloride in dichloromethane
-78 deg C, 2 h, then RT, 48 h;
参考文献
Raddo, Pasquale Di; Harvey, Ronald G.
Tetrahedron Letters, 1988 , vol. 29, # 32 p. 3885 - 3886
反应条件
tris(pentafluorophenyl)-borane in dichloromethane
T=-78°C; 4 h;
参考文献
Ishihara, Kazuaki; Hanaki, Naoyuki; Funahashi, Miyuki; Miyata, Mayumi; Yamamoto, Hisashi
Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 6 p. 1721 - 1730
反应条件
boron trifluoride diethyl etherate in diethyl ether; dichloromethane
T=-78°C; 3 h;
参考文献
Duhamel, P.; Hennequin, L.; Poirier, J. M.; Tavel, G.; Vottero, C.
Tetrahedron, 1986 , vol. 42, # 17 p. 4777 - 4786
反应条件
boron trifluoride diethyl etherate in diethyl ether; dichloromethane
-70 deg C to -30 deg C;
参考文献
Duhamel, Pierre; Poirier, Jean-Marie; Tavel, Gilbert
Tetrahedron Letters, 1984 , vol. 25, # 1 p. 43 - 46
反应条件
1: [Ir(COD)(PPh3)2]OTf-H2 / CH2Cl2 / 12 h / 70 °C
2: HCl / methanol
View Scheme
参考文献
Matsuda, Isamu; Makino, Tatsuya; Hasegawa, Yuki; Itoh, Kenji
Tetrahedron Letters, 2000 , vol. 41, # 9 p. 1409 - 1412
