2-溴-4,5-二甲基吡啶合成路线 （共 2 条）
反应条件
1: With n-butyllithium; 2-(dimethylamino)-ethanol in hexane
T=0°C;
2: With carbon tetrabromide in tetrahydrofuran; hexane
T=-78 - 20°C;
参考文献
Bayer Scherring Pharma Aktiengellschaft
Patent: US2010/93803 A1, 2010 ;
Location in patent: Page/Page column 23 ;
US 20100093803 A1
反应条件
1: With n-butyllithium; 2-(dimethylamino)-ethanol in hexane
T=0°C; 1 h;
2: With carbon tetrabromide in tetrahydrofuran; hexane
T=-78°C; 1 h; Further stages.;
参考文献
Kaminski, Thomas; Gros, Philippe; Fort, Yves
European Journal of Organic Chemistry, 2003 , # 19 p. 3855 - 3860
