反应条件
1: 81 percent / n-BuLi / benzene; hexane / 0 - 20 °C
2: 95 percent / PhSH, air / 0.33 h / 95 - 100 °C
3: LiAlH4 / tetrahydrofuran / 3 h / Ambient temperature
4: 1.) (COCl)2, DMSO, 2.) Et3N / 1.) CH2Cl2. -65 deg C, 1 h, 2.) CH2Cl2, -60 deg C 30 min
5: 1.) LDA / 1.) THF, hexane, -78 deg C, 10 min, 2.) THF, hexane, -78 to -20 deg C, 4 h
6: 90 percent / KOH / ethanol; H2O / Ambient temperature
7: (COCl)2 / benzene / 1 h / Heating
8: Et3N / diethyl ether / -5 - 20 °C
View Scheme
参考文献
Rotherham, Lloyd W.; Edward Semple
Journal of Organic Chemistry, 1998 , vol. 63, # 19 p. 6667 - 6672
