3-(4-溴苯基)-6-氯哒嗪合成路线 （共 9 条）
反应条件
trichlorophosphate
T=100°C; 16 h;
参考文献
ABBOTT LABORATORIES
Patent: WO2006/65233 A1, 2006 ;
Location in patent: Page/Page column 76 ;
反应条件
in water; trichlorophosphate
参考文献
Abbott Laboratories
Patent: US2005/245531 A1, 2005 ;
US 20050245531 A1
反应条件
in trichlorophosphate
参考文献
American Cyanamid Company
Patent: US4092311 A1, 1978 ;
反应条件
trichlorophosphate
3 h; Heating;
参考文献
Sayed, G. H.; Sayed, M. A.; Shaaban, S. S.; Mahmoud, M. R.
Egyptian Journal of Chemistry, 2000 , vol. 43, # 1 p. 17 - 29
反应条件
1: 67 percent / benzene / 10 h / Heating
2: 80 percent / hydrazine hydrate / ethanol / Heating
3: 82 percent / POCl3 / 3 h / Heating
View Scheme
参考文献
Sayed, G. H.; Sayed, M. A.; Shaaban, S. S.; Mahmoud, M. R.
Egyptian Journal of Chemistry, 2000 , vol. 43, # 1 p. 17 - 29
反应条件
1: 80 percent / hydrazine hydrate / ethanol / Heating
2: 82 percent / POCl3 / 3 h / Heating
View Scheme
参考文献
Sayed, G. H.; Sayed, M. A.; Shaaban, S. S.; Mahmoud, M. R.
Egyptian Journal of Chemistry, 2000 , vol. 43, # 1 p. 17 - 29
反应条件
1: AlCl3, aluminium chloride / Reflux
2: sodium acetate; hydrazine hydrate / methanol / 6 h / Reflux
3: trichlorophosphate / 6 h / Heating
View Scheme
参考文献
Islam, Mojahidul; Siddiqui, Anees A.
Acta Poloniae Pharmaceutica - Drug Research, 2010 , vol. 67, # 5 p. 555 - 562
反应条件
1: sodium acetate; hydrazine hydrate / methanol / 6 h / Reflux
2: trichlorophosphate / 6 h / Heating
View Scheme
参考文献
Islam, Mojahidul; Siddiqui, Anees A.
Acta Poloniae Pharmaceutica - Drug Research, 2010 , vol. 67, # 5 p. 555 - 562
反应条件
hydrazine hydrate in butan-1-ol
6 h; Reflux;
参考文献
El-Mobayed, Medhat M.; Hussein, Ahmed M.; Mohlhel, Wafia M.
Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 3 p. 534 - 537
