2,6-二氯-3-(三氟甲基)苯氨合成路线 （共 3 条）
反应条件
hydrogen; nickel in methanol
T=20°C;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH; IRM LLC
Patent: WO2006/420 A1, 2006 ;
Location in patent: Page/Page column 283 ;
WO 2006/000420 A1
反应条件
N-chloro-succinimide
参考文献
The Dow Chemical Company
Patent: US4755212 A1, 1988 ;
反应条件
tert.-butylhydroperoxide; copper(II) bis(trifluoromethanesulfonate) in water; acetonitrile
T=20°C; 2.5 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Langlois, Bernard R.; Laurent, Eliane; Roidot, Nathalie
Tetrahedron Letters, 1991 , vol. 32, # 51 p. 7525 - 7528
