(3aalpha,4beta,6aalpha)-N,N-二[2-(二苯基膦基)乙基]六氢-2-氧代-1H-噻吩并[3,4-d)咪唑-4-戊酰胺合成路线 (共 2 条)
反应条件
triethylamine in N,N-dimethyl-formamide
60 h; Ambient temperature;
参考文献
Nuzzo, Ralph G.; Haynie, Sharon L.; Wilson, Michael E.; Whitesides, George M.
Journal of Organic Chemistry, 1981 , vol. 46, # 14 p. 2861 - 2867
反应条件
1: 90 percent / 1.) potassium tert-butoxide 2.) 2N HCl / tetrahydrofuran / 16 h / Heating
2: 83 percent / Triethylamine / dimethylformamide / 60 h / Ambient temperature
View Scheme
参考文献
Nuzzo, Ralph G.; Haynie, Sharon L.; Wilson, Michael E.; Whitesides, George M.
Journal of Organic Chemistry, 1981 , vol. 46, # 14 p. 2861 - 2867