N-Boc-L-苯丙氨醇合成路线 （共 89 条）
反应条件
in dichloromethane Acylation;
参考文献
Kerherve, Jennifer; Botuha, Candice; Dubois, Joelle
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 10 p. 2214 - 2222
反应条件
sodium tetrahydroborate in tetrahydrofuran; methanol T=50 - 55°C;
参考文献
Soai; Oyamada; Takase
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 8 p. 2327 - 2328
反应条件
hydrogen; palladium on activated charcoal in ethylene glycol dimethyl ether T=20°C; Reduction; P=3800 Torr; 3 h;
参考文献
Falorni, Massimo; Giacomelli, Giampaolo; Porcheddu, Andrea; Taddei, Maurizio
Journal of Organic Chemistry, 1999 , vol. 64, # 24 p. 8962 - 8964
反应条件
sodium tetrahydroborate; lithium chloride in tetrahydrofuran T=20°C; Inert atmosphere;
参考文献
Spaeth, Andreas; Gonschor, Janina; Koenig, Burkhard
Monatshefte fur Chemie, 2011 , vol. 142, # 12 p. 1289 - 1308
反应条件
sodium tetrahydroborate; 2-(6-nitro-1-oxy-benzotriazol-3-yl)-1,1,3,3-Me4-uronium*PF6; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C; 0.5 h;
参考文献
Srivastava, Tumul; Srivastava, Tushar K.; Haq; Katti, Seturam B.
Journal of Chemical Research - Part S, 2003 , # 8 p. 516 - 517
反应条件
potassium hydrogensulfate in methanol T=20°C; 1.5 h;
参考文献
Kishore Kumar; Baskaran, Sundarababu
Journal of Organic Chemistry, 2005 , vol. 70, # 11 p. 4520 - 4523
反应条件
sodium tetrahydroborate in methanol T=20°C; 0.25 h; Inert atmosphere;
参考文献
Holan, Martin; Jahn, Ullrich
Organic Letters, 2014 , vol. 16, # 1 p. 58 - 61
反应条件
sodium hydroxide in dichloromethane; water T=20°C; 24 h;
参考文献
Ji, Haitao; Li, Huiying; Martasek, Pavel; Roman, Linda J.; Poulos, Thomas L.; Silverman, Richard B.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 3 p. 779 - 797
反应条件
diisobutylaluminium hydride in hexane; dichloromethane T=-78°C; 0.1 h;
参考文献
Camplo; Niddam; Barthelemy; Faury; Mourier; Simon; Charvet; Trabaud; Graciet; Chermann; Kraus
European Journal of Medicinal Chemistry, 1995 , vol. 30, # 10 p. 789 - 800
反应条件
hydrogen; {(1,5-cyclooctadiene)Rh(1,2-bis((2S,5S)-2,5-diethylphospholano)benzene)}triflate in tetrahydrofuran T=20 - 25°C; Catalytic hydrogenation; P=1551.44 Torr; 12 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 40, # 36 p. 6685 - 6688
