N-Boc-L-苯丙氨醇合成路线 （共 89 条）
反应条件
sodium tetrahydroborate in ethylene glycol dimethyl ether; water 0.166667 h; Ambient temperature;
参考文献
Fehrentz, Jean-Alain; Califano, Jean-Christophe; Amblard, Muriel; Loffet, Albert; Martinez, Jean
Tetrahedron Letters, 1994 , vol. 35, # 4 p. 569 - 572
反应条件
methanol; C17H23BN2O T=25°C; P=760.051 Torr; 13 h; Inert atmosphere; chemoselective reaction;
参考文献
Oishi, Shunsuke; Saito, Susumu
Angewandte Chemie - International Edition, 2012 , vol. 51, # 22 p. 5395 - 5399
反应条件
sodium tetrahydroborate; iodine in tetrahydrofuran T=20°C; Reduction;
参考文献
Naqvi; Bhattacharya; Haq
Journal of Chemical Research - Part S, 1999 , # 7 p. 424 - 425
反应条件
triethylamine in 1,4-dioxane; water T=20°C; 3.5 h;
参考文献
Konda, Yaeko; Takahashi, Yukihiro; Arima, Shiho; Sato, Noriko; Takeda, Kazuyoshi; Dobashi, Kazuyuki; Baba, Masanori; Harigaya, Yoshihiro
Tetrahedron, 2001 , vol. 57, # 20 p. 4311 - 4321
反应条件
sodium hydrogencarbonate in N-methyl-acetamide
反应条件
lithium borohydride in tetrahydrofuran
反应条件
methanol; sodium tetrahydroborate T=0°C; 0.333333 h; Yield given;
参考文献
Synthesis, , p. 299 - 301
反应条件
sodium tetrahydroborate in methanol 3 h; 0 deg C -> r.t.;
参考文献
Reddy, G. Vidyasagar; Rao, G. Venkat; Iyengar
Tetrahedron Letters, 1999 , vol. 40, # 13 p. 2653 - 2656
反应条件
1: With acetyl chloride in methanol 2: With di-tert-butyl dicarbonate; triethylamine in tetrahydrofuran
参考文献
Harvey, Joanne E.; Kenworthy, Martin N.; Taylor, Richard J. K.
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2467 - 2471
反应条件
1: aq. NaOH / dioxane / 20 °C 2: NEt3 / tetrahydrofuran / -10 °C 3: NaBH4 / H2O / 0 °C View Scheme
参考文献
Bioorganic and medicinal chemistry letters, , vol. 14, # 1 p. 275 - 278
