[(苯基甲亚基)氨基]乙酸甲酯合成路线 （共 4 条）
反应条件
1: With lithium tert-butylate in toluene T=20°C; 1.5 h; 2: With water in tert-butyl methyl ether; toluene 3: With hydrogenchloride; sodium hydroxide; sodium chloride more than 3 stages;
参考文献
PHENOMIX CORPORATION
Patent: WO2008/86161 A1, 2008 ;
Location in patent: Page/Page column 50 ;
WO 2008/086161 A1
反应条件
silver(I) acetate; 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
T=20°C; 34 h; Inert atmosphereReflux;
参考文献
Kudryavtsev, Konstantin V.; Ivantcova, Polina M.; Churakov, Andrei V.; Vasin, Victor A.
Tetrahedron Letters, 2012 , vol. 53, # 33 p. 4300 - 4303
反应条件
1: With triethylamine; triphenylphosphine; [Cu(I)(CH3CN)4]PF6 in tetrahydrofuran
T=20°C; 5 h;
2: With 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
T=20°C; 0.5 h; Further stages.;
参考文献
Lopez-Perez, Ana; Robles-Machin, Rocio; Adrio, Javier; Carretero, Juan Carlos
Angewandte Chemie - International Edition, 2007 , vol. 46, # 48 p. 9261 - 9264
反应条件
1: With triethylamine; triphenylphosphine; [Cu(I)(CH3CN)4]PF6 in tetrahydrofuran
T=20°C; 5 h;
2: With 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
T=20°C; 0.5 h; Further stages.;
参考文献
Lopez-Perez, Ana; Robles-Machin, Rocio; Adrio, Javier; Carretero, Juan Carlos
Angewandte Chemie - International Edition, 2007 , vol. 46, # 48 p. 9261 - 9264
