双环[3.3.1]壬-3-烯合成路线 （共 22 条）
反应条件
1: NBS, (PhCO)2O2 / CCl4 / Heating 2: aq. KOH / dioxane / Heating 3: MnO2 View Scheme
参考文献
Davies,J.M.; Graham,S.H.
Journal of the Chemical Society [Section] C: Organic, 1968 , p. 2040 - 2041
反应条件
(i) NaBH4, BF3-Et2O, (ii) aq. NaOH, aq. H2O2; Multistep reaction;
参考文献
Schaefer,J.P. et al.
Journal of Organic Chemistry, 1967 , vol. 32, p. 1372 - 1378
反应条件
1: H2 / PtO2 / ethanol
2: NaH / 1,2-dimethoxy-ethane
3: aq. KOH / methanol
4: H2SO4 / 1,2-dichloro-ethane
5: Al(OiPr)3
6: aq. KOH / ethanol
7: diethyl ether
8: Py
9: aq. KOH, Py / ethanol
10: KOtBu / dimethylsulfoxide
11: MeLi / diethyl ether
View Scheme
参考文献
Marshall,J.A.; Faubl,H.
Journal of the American Chemical Society, 1970 , vol. 92, # 4 p. 948 - 955
反应条件
1: NaH / 1,2-dimethoxy-ethane
2: H2 / PtO2 / ethanol
3: NaH / 1,2-dimethoxy-ethane
4: aq. KOH / methanol
5: H2SO4 / 1,2-dichloro-ethane
6: Al(OiPr)3
7: aq. KOH / ethanol
8: diethyl ether
9: Py
10: aq. KOH, Py / ethanol
11: KOtBu / dimethylsulfoxide
12: MeLi / diethyl ether
View Scheme
参考文献
Marshall,J.A.; Faubl,H.
Journal of the American Chemical Society, 1970 , vol. 92, # 4 p. 948 - 955
反应条件
methyllithium in diethyl ether
参考文献
Marshall,J.A.; Faubl,H.
Journal of the American Chemical Society, 1970 , vol. 92, # 4 p. 948 - 955
反应条件
1: H2SO4 / 1,2-dichloro-ethane
2: Al(OiPr)3
3: aq. KOH / ethanol
4: diethyl ether
5: Py
6: aq. KOH, Py / ethanol
7: KOtBu / dimethylsulfoxide
8: MeLi / diethyl ether
View Scheme
参考文献
Marshall,J.A.; Faubl,H.
Journal of the American Chemical Society, 1970 , vol. 92, # 4 p. 948 - 955
反应条件
1: Al(OiPr)3
2: aq. KOH / ethanol
3: diethyl ether
4: Py
5: aq. KOH, Py / ethanol
6: KOtBu / dimethylsulfoxide
7: MeLi / diethyl ether
View Scheme
参考文献
Marshall,J.A.; Faubl,H.
Journal of the American Chemical Society, 1970 , vol. 92, # 4 p. 948 - 955
反应条件
phosphoric acid
T=160 - 180°C;
参考文献
Schaefer,J.P. et al.
Journal of Organic Chemistry, 1967 , vol. 32, p. 3963 - 3969
反应条件
potassium hydroxide; hydrazine hydrate in diethylene glycol
参考文献
Marvell,E.N. et al.
Journal of Organic Chemistry, 1970 , vol. 35, p. 391 - 396
反应条件
1: (i) nPrMgBr, TiCl4, THF, (ii) /BRN= 1900390/
2: SOCl2, Py / benzene
3: AlCl3 / 1,2-dichloro-ethane
4: N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether
View Scheme
参考文献
Marvell,E.N. et al.
Journal of Organic Chemistry, 1970 , vol. 35, p. 391 - 396
