2-氮杂双环[2.2.1]-5-庚烯合成路线 （共 3 条）
反应条件
sodium carbonate in water T=0°C; 2 h; Yield given;
参考文献
Carroll, F. Ivy; Abraham, Phillip; Chemburkar, Sanjay; He, Xu-Chang; Mascarella, S. Wayne; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2184 - 2191
反应条件
in tetrahydrofuran; diethyl ether 14 h; Ambient temperature; Yield given;
参考文献
Coleman, Paul J.; Schreier, John D.; McGaughey, Georgia B.; Bogusky, Michael J.; Cox, Christopher D.; Hartman, George D.; Ball, Richard G.; Harrell, C. Meacham; Reiss, Duane R.; Prueksaritanont, Thomayant; Winrow, Christopher J.; Renger, John J.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2311 - 2315
反应条件
1: Na2CO3 / H2O / 2 h / 0 °C 2: 1.) Hg(OAc)2, 2.) 0.5 M NaBH4 in 3 N NaOH / 1.) H2O, THF, RT, 12 h, 2.) H2O, THF, 0 deg C 3: 62 percent / Jones reagent / acetone / 3 h / Ambient temperature View Scheme
参考文献
Carroll, F. Ivy; Abraham, Phillip; Chemburkar, Sanjay; He, Xu-Chang; Mascarella, S. Wayne; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2184 - 2191
