2,3-二氢-8-甲氧基-4H-1-苯并噻喃-4-酮合成路线 （共 3 条）
反应条件
sulfuric acid
T=5°C; Friedel Crafts intramolecular acylation;
参考文献
Guo, Dexiang; Liu, Yajing; Li, Ting; Wang, Nan; Zhai, Xin; Hu, Chun; Gong, Ping
Science China Chemistry, 2012 , vol. 55, # 3 p. 347 - 351
反应条件
hydrogenchloride in benzene
参考文献
Toray Industries, Inc.
Patent: US5565440 A1, 1996 ;
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 60 °C / Inert atmosphere
1.2: 1.5 h / 60 °C / Inert atmosphere
2.1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 0.5 h / 0 °C
2.2: 2 h / 0 °C
View Scheme
参考文献
MERCK SERONO S.A.; GAILLARD, Pascale; JEANCLAUDE-ETTER, Isabelle; POMEL, Vincent; SEBILLE, Eric; JEYAPRAKASHNARAYANAN, Seenisamy; MUZERELLE, Mathilde
Patent: WO2011/58149 A1, 2011 ;
WO 2011/058149 A1
