1,1,4,4-四甲基-1,2,3,4-四氢萘合成路线 （共 27 条）
反应条件
1: acetyl chloride With AlCl3, aluminium chloride in dichloromethane T=0°C; 0.0833333 h; 2: 1,2,3,4-tetrahydro-1,1,4,4-tetramethyl naphthalene in dichloromethane T=20°C; 3 h;
参考文献
Tsang, Kwok Yin; Sinha, Santosh; Liu, Xiaoxia; Bhat, Smita; Chandraratna, Roshantha A.
Patent: US2005/148590 A1, 2005 ;
Location in patent: Page/Page column 12; 13 ;
参考文献
Hoffmann-La Roche
Patent: DE2854354 , 1979 ;
Chem.Abstr., 1979 , vol. 91, # 140631
反应条件
2: LiAlH4 / diethyl ether; tetrahydrofuran
View Scheme
参考文献
Hoffmann-La Roche
Patent: DE2854354 , 1979 ;
Chem.Abstr., 1979 , vol. 91, # 140631
反应条件
2: LiAlH4 / diethyl ether; tetrahydrofuran
3: (i) NaH, DMF, (ii) /BRN= 969135/
View Scheme
参考文献
Hoffmann-La Roche
Patent: DE2854354 , 1979 ;
Chem.Abstr., 1979 , vol. 91, # 140631
参考文献
Hoffmann-La Roche
Patent: DE2854354 , 1979 ;
Chem.Abstr., 1979 , vol. 91, # 140631
反应条件
sulfuric acid; nitric acid
参考文献
Wood,T.F. et al.
Journal of Organic Chemistry, 1963 , vol. 28, p. 2248 - 2255
反应条件
in dichloromethane
T=0 - 20°C; 1.08333 h;
参考文献
Merck Patent Gesellschaft MIT Beschrankter Haftung
Patent: US2012/252815 A1, 2012 ;
Location in patent: Page/Page column 76 ;
