N,N,N',N',N'',N''-hexamethylphosphoric triamide T=240°C; 1.5 h;

1: Methyltriphenylphosphonium bromide With n-butyllithium in diethyl ether; hexane 1 h; Inert atmosphere; 2: 1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-one in diethyl ether; hexane T=20°C; Wittig reaction; 24 h; Inert atmosphere;

2,2,2-trifluoroethanol; sodium perchlorate; water T=25°C; Rate constant;

1: 95.1 percent / Mg / diethyl ether / 0.5 h / Ambient temperature 2: 81.5 percent / hexamethylphosphoric triamide / 1.5 h / 240 °C View Scheme

1: 1.) Mg / 2.) ether 2: 79 percent / KHSO4 / 140 °C / 100 Torr View Scheme