4-(1H-吲哚-3-基)丁胺合成路线 （共 3 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
3 h; Heating;
参考文献
Mewshaw, Richard E.; Zhou, Dahui; Zhou, Ping; Shi, Xiaojie; Hornby, Geoffrey; Spangler, Taylor; Scerni, Rosemary; Smith, Deborah; Schechter, Lee E.; Andree, Terrance H.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 15 p. 3823 - 3842
反应条件
1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 1.5 h / 20 °C
1.2: 96 percent / NH3(g) / tetrahydrofuran / 2.5 h / 20 °C
2.1: 75 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating
View Scheme
参考文献
Mewshaw, Richard E.; Zhou, Dahui; Zhou, Ping; Shi, Xiaojie; Hornby, Geoffrey; Spangler, Taylor; Scerni, Rosemary; Smith, Deborah; Schechter, Lee E.; Andree, Terrance H.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 15 p. 3823 - 3842
反应条件
1: 83 percent / ammonia / methanol / 48 h / 20 °C
2: LiAlH4 / tetrahydrofuran / 24 h / 20 °C
View Scheme
参考文献
Doernyei, Gabor; Incze, Maria; Kajtar-Peredy, Maria; Szantay, Csaba
Collection of Czechoslovak Chemical Communications, 2002 , vol. 67, # 11 p. 1669 - 1680
