3-氟-4-碘吡啶-2-甲腈合成路线 (共 1 条)
反应条件
1: With n-butyllithium; diisopropylamine; lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 0.583333 h;
2: With iodine in tetrahydrofuran
0.75 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; BALOG, James Aaron; HUANG, Audris; VELAPARTHI, Upender; LIU, Peiying
Patent: WO2013/49263 A1, 2013 ;
Location in patent: Paragraph 00296; 00297 ;