5-溴-3-氟吡啶-2-羧酸合成路线

GLAXOSMITHKLINE LLC; ADAMS, Nicholas, David; CHAUDHARI, Amita, M.; KIESOW, Terence, John; McSHERRY, Allison, K.; MOORE, Michael, Lee; PARRISH, Cynthia, Ann; REIF, Alexander, Joseph; RIDGERS, Lance, Howard
Patent: WO2014/8223 A2, 2014 ;

669066-91-55-溴-3-氟吡啶-2-羧酸+

6638-79-5二甲羟胺盐酸盐

669066-92-6

参考文献

JERINI AG
Patent: WO2009/36996 A2, 2009 ;
Location in patent: Page/Page column 106 ;
WO 2009/036996 A2

669066-91-55-溴-3-氟吡啶-2-羧酸+

1117-97-1N-甲基-N-甲氧基胺盐酸盐

669066-92-6

参考文献

Kuduk, Scott D.; DiPardo, Robert M.; Chang, Ronald K.; Di Marco, Christina N.; Murphy, Kathy L.; Ransom, Richard W.; Reiss, Duane R.; Tang, Cuyue; Prueksaritanont, Thomayant; Pettibone, Douglas J.; Bock, Mark G.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 13 p. 3608 - 3612